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Jul
17

Researchers suggest change of target in latent TB screening

Researchers have published an article in the medical journal Thorax, suggesting improvements to the way people moving to the UK are screened for tuberculosis (TB). Currently, screening for latent TB is based on TB infection rates in the country a person comes from. However, the researchers say that this alone “does not accurately predict the number of active cases subsequently arising in the UK”. They instead suggest targeting screening based on infection rates in people from a particular country once they are in the UK.

Access the article online on the Thorax website


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Jul
17

Genetics of TB bacteria mapped

Research published in the journal Nature has mapped out the genetics of the regulatory network of Mycobacterium tuberculosis, the bacteria which cause tuberculosis. The focus of the research was on the genes that control how the bacteria respond to environmental changes. The work is being hailed as a “landmark” discovery and the researchers hope that a clearer understanding of the genetic makeup of the bacteria will allow other scientists to design more effective ways to target the disease.

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Access the journal abstract on the Nature website


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Jul
17

Ethnic differences affect immune response to TB

New research published in the journal, PLOS Pathogens, suggests that people from different ethnic groups may show different immune responses to the bacteria which cause TB. The study was led by researchers at Queen Mary, University of London, in collaboration with the Medical Research Council's National Institute for Medical Research (NIMR). As immune response is often used to diagnose TB, and to see how well treatment is working, the researchers say that new tests developed will have to be checked in different ethnic groups to make sure they are accurate.

Read more:
University of London press release
Article in the New Scientist
Journal article in PLOS Pathogens

  • We need people – people like those in TB Alert, who are focused and ambitious and care for people at grass roots in the UK, India and Africa. Dr Lucica Ditiu, Executive Secretary of the Stop TB Partnership

  • We cannot win the battle against AIDS if we do not also fight TB. TB is too often a death sentence for people with AIDS. It does not have to be this way. We have known how to cure TB for more than 50 years. What we have lacked is the will and the resources to quickly diagnose people with TB and get them the treatment they need. Nelson Mandela

  • I am very impressed by the work done by TB Alert, that is why I wanted to spread the message...I am one of those that did think that TB had been eradicated...and suddenly it is back in a very big way! Baroness Joan Bakewell, explaining why she supports TB Alert

  • TB is the child of poverty – and also its parent and provider. TB Alert's Patron, Archbishop Desmond Tutu

  • TB Alert are passionate in their work to stamp out TB in the UK and alleviate the problems of people with TB. Alan Higgins, Director of Public Health, Oldham

  • TB Alert allowed me to regain a purpose to live. People who listened, understood and never judged. I am now proud to be part of the team which is able to offer peer support to others. Steve, TB Action Group member

  • TB Alert UK respects partnership work. Chennupati Vidya, President  of TB Alert partner, VMM